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Antiretroviral Therapy for HIV Infection in Adults and Adolescents. Recommendations for a Public Health Approach. 2010 Revision

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The guidance will dramatically increase the number of people with HIV who qualify for treatment

Published by WHO 2010
ISBN 978 92 4 159976 4

The guidance, with its emphasis on earlier treatment, will dramatically increase the number of people with HIV who qualify for treatment, from an estimated 10 million to an estimated 15 million. WHO assembled a panel of experts to discuss what these guidelines will mean, how acceptable they are to the community and what will it take to implement them.

The new guidance, which had an advance-release towards the end of last year, contains four key changes.

-It promotes earlier treatment, recommending starting HIV treatment at 350 cells or below.
-It recommends moving to more patient-friendly and less toxic regimens, phasing out stavudine (d4T), which is more toxic than initially thought
-It recommends starting coinfected people with TB (or hepatitis B if it requires treatment) on ART earlier, regardless of the CD4 count
-It acknowledges the prevention benefits of treatment.

Download Antiretroviral therapy for HIV infection in adults and adolescents (PDF, 1.77MB, 156 pg)